PHILADELPHIA - At least five people were killed and dozens injured after a train derailed and overturned in Philadelphia late on Tuesday.
Emergency personnel said six of the injured were in critical condition and 53 others were less critically hurt amid chaotic scenes after at least seven train cars, including the engine car, were crushed, turned over on their side or left upside down.
"It is an absolute disastrous mess. I have never seen anything like this in my life and most personnel will say that, as well," Philadelphia Mayor Michael Nutter told reporters.
But Nutter warned that the casualty and injury estimates were only preliminary, hinting at the potential for a higher toll.
Hydraulic tools had to be used to remove passengers from some of the most badly damaged train cars, emergency personnel said.
Initial reports had indicated that 10 of the train cars were affected by the accident.
Hundreds of emergency personnel, including firefighters and police, were deployed.
The Philadelphia Fire Department launched a large-scale operation to assist the 243 people aboard Amtrak Train 188 travelling from Washington DC to New York.
The US Department of Homeland Security, the Southeastern Pennsylvania Transportation Authority, the Amtrak national rail service and others were involved in the search and rescue operation.
The National Transportation Safety Board said it was gathering information about the derailment.
Emergency personnel declined to speculate on the causes of the crash.
In a brief statement, Amtrak said all service had been suspended between New York and Philadelphia in the heavily-trafficked northeast corridor.